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The lawful status is not really crystal clear. It truly is legal in lots of international locations as a means for research and scientific do the job.
Q. How can this compound's pharmacological profile be optimized to reduce Unwanted effects even though retaining analgesia?
Comparative Scientific tests : In head-to-head trials, this compound outperformed each morphine and oxycodone in terms of efficacy even though eliciting much less side effects, making it a promising candidate for ache administration tactics in opioid-dependent populations
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Chronic Administration Scientific studies : Mice taken care of using this compound showed no considerable withdrawal indicators when compared to All those addressed with morphine, suggesting a decreased probable for dependence
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Substitution: Nucleophilic substitution reactions is often done employing reagents like sodium methoxide or potassium tert-butoxide.
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